Autoimmune diseases (AID) are convoluted pathologies characterized by immunologic malfunction and intolerance to self-molecules,1 genetic background is implicated but alone is insufficient for the development of most forms of autoimmunity.2
Research findings point to the role that human endogenous retroviruses and adjuvants play in AID.3
Type 1 Diabetes Mellitus (T1DM) is one of the most prevalent of over eighty identified AID4 and accounts for 5-10% of all diabetes diagnoses.5
An organ-specific disease involving response against pancreatic β cells, T1DM often occurs concomitantly with other AID - an estimated > 90% of patients also have autoimmune thyroid disease.6
A serious and life-threatening disease requiring lifelong dependency upon insulin injections, T1DM is responsible for 85% of diabetes in under 20year old’s7 and typically classified as a disease of childhood and adolescence however 40% of diagnoses are made in adults aged over 30years old.8
A seven-year observational study of fifteen T1DM patients prescribed individualized homeopathic medicine reported ‘twelve cases (80% of patients) had improved fasting blood sugars and haemoglobin A1c, reducing the need for insulin, with the parents of juvenile patients also reporting changes in disposition with notably improved behaviours, while adult patients cited feelings of inner calm, and experienced greater self-control.’9
‘Use of complementary and alternative medicine (CAM) in children with type 1 diabetes is less common than that documented for adults. Parents using CAM do not question the need for insulin. When using CAM, improved well-being and quality of life are important considerations where CAM can have a role.’10
‘CAM, mostly herbal, is frequently used among children with T1DM in North India and has detrimental effects on glycemic control. This information should be used during diabetes education to avoid medical emergencies related to sub-optimal insulin dosing.’11
‘The use of CAM in children with T1DM is relatively common. Greater insight into the influences of CAM in the management and treatment of patients with T1DM could be achieved through assessment by diabetes care teams on the use of CAM in children with T1DM, and monitoring for any potential positive or negative effects.’12
Positive laboratory-revealed homeopathic medicine actions in models of inflammation and immunity, though often small, are not negligible findings as even a minor influence can orient the entire system in the disease process, becoming a deciding factor in the final reaction. Inflammation and the immune system are notably susceptible to minor influence because the same mechanisms can be implemented to cure or to self-destruct.13
The immune system strives to maintain optimal equilibrium under stress, however when a stressor cannot be nullified on the peripheral level, defence is relegated to a deeper, more vital organ or system
It is in this way that chronic degenerative disease begins, compromising overall wellbeing14
Evidenced for example, by rising rates of AID while infectious disease declines.15
( The above are excerpts from one of my BSc(hons) submission papers (2021) - the full (weighty) text (which the first marker failed by the way) is available in the archives Homeopathy & Type 1 Diabetes Mellitus)
The effort of the defense system to overcome diseased states is highly individualized and comprised of idiosyncrasies in the disposition of the person and modalities of the symptoms. This is the basic understanding in homeopathy, the principle upon which the treatment is understood and designed.16
Iris Bell, MD, PhD,17 concludes …
‘Every homeopathic medicine is a complex nano-scale system involving multiple inter-connected, interacting components, and emergent properties.
Simillimum individualization derives from formation of a unique personalized protein corona shell adsorbed to the reactive surface of the homeopathic nano-structures on contact with the recipient's body fluids.
Low doses of such complex nano-structures initiate the adaptive processes of hormesis to mobilize endogenous healing of a disease state.
The capacity for self-organization and self-similarity in complex systems is the key to future research on the nature of homeopathic medicines and systemic healing during individualized homeopathic treatment.’ 18
(The above taken from Homeopathy & the Defense system in the archives)19
Just some of the excellent contributions to homeopathy by Dr. Iris Bell:
Homeopathy & Hormonal imbalance22
Homeopathy, Athletes, & Antibiotic Resistance23
‘In contrast to frequent claims, the available MAs of homoeopathy in placebo-controlled randomised trials for any indication show significant positive effects beyond placebo. Compared to other medical interventions, the quality of evidence for efficacy of homoeopathy was similar or higher than for 90% of interventions across medicine.25
Accordingly, the efficacy evidence from placebo-controlled randomised trials provides no justification for regulatory or political actions against homoeopathy in health-care systems.’26
Smith & Germolec, 1999. Introduction to immunology and autoimmunity. Environ Health Perspectives. Oct; 107 Suppl 5(Suppl 5):661-5. Available from: https://pubmed.ncbi.nlm.nih.gov/10502528/
Meda et al., 2011. The epigenetics of autoimmunity. Cellular and Molecular Immunology. May;8(3):226-36. Available from: https://pubmed.ncbi.nlm.nih.gov/21278766/
Homeopathy & Type 1 Diabetes Mellitus
Autoimmune diseases (AID) are convoluted pathologies characterized by immunologic malfunction and intolerance to self-molecules(1), genetic background is implicated but alone is insufficient for the development of most forms of autoimmunity.(2) Findings point to the role that human endogenous retroviruses(3-6) and adjuvants(7-12) play in AID aetiopathog…
Nexø et al., 2016. Are human endogenous retroviruses triggers of autoimmune diseases? Unveiling associations of three diseases and viral loci. Immunological research. 64(1), 55–63. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726719/
Kahanovitz et al., 2017. Type 1 Diabetes - A Clinical Perspective. Point of care. 16(1), 37–40. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606981/
Kawasaki, 2014. Type 1 diabetes and autoimmunity. Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology. 23 (4), 99–105. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219937/
Rodríguez, 2019. Unexpected viral behavior linked to type 1 diabetes in highrisk children [online]. Baylor College of Medicine, Houston. Available from: https://blogs.bcm.edu/2019/12/19/from-the-labs-unexpected-viral-behavior-linked-totype-1-diabetes-in-high-risk-children/
Thomas et al., 2017. Frequency and phenotype of type 1 diabetes in the first six decades of life: a crosssectional, genetically stratified survival analysis from UK Biobank. The Lancet Diabetes & Endocrinology [online]. Volume 6, Issue 2, p122-129. Available from:https://www.thelancet.com/journals/landia/article/PIIS2213-8587(17)30362- 5/fulltext#%20
Sadeghi, S. 2016. Assessment of homeopathic remedies effects in type 1 diabetics. Hilaris; Alternative and Integrative Medicine. 5th International Conference and Exhibition on Natural & Alternative Medicine, September 05-07, 2016 Beijing, China. Available from: https://www.hilarispublisher.com/proceedings/assessment-ofhomeopathic-remedies-effects-in-type-1-diabetics-28227.html
Dannemann K, Hecker W, Haberland H, Herbst A, Galler A, Schäfer T, Brähler E, Kiess W, Kapellen TM. 2008 Use of complementary and alternative medicine in children with type 1 diabetes mellitus - prevalence, patterns of use, and costs. Pediatr Diabetes. Jun;9(3 Pt 1):228-35. PMID: 18331412.
Walia P, Rohilla L, Dayal D. 2023. Practice of complementary and alternative medicine use in North Indian children with type 1 diabetes: an exploratory study. Diabetol Int. Sep 22;15(2):170-176. PMCID: PMC10959897.
Lemay JF, Amin A, Pacaud D. 2011. Complementary and alternative medicine use in children and adolescents with type 1 diabetes. Paediatr Child Health. Oct;16(8):468-72.PMCID: PMC3202385.
Bellavite et al., 2006. Immunology and homeopathy. 2. Cells of the immune system and inflammation. Evidence-based complementary and alternative medicine: eCAM. 3 (1), 13–24. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1375241/
Vithoulkas, G and Carlino, S. 2010. The “continuum” of a unified theory of diseases. Medical Science Monitor [online]. 16(2): SR7-15. Available from: https://medscimonit.com/abstract/index/idArt/878341
Bach et al., 2018. The hygiene hypothesis in autoimmunity: the role of pathogens and commensals. Nature Reviews, Immunology. Feb; 18 (2): 105-120. Available from: https://pubmed.ncbi.nlm.nih.gov/29034905/
Mahesh S, Jaggi L, Jaggi A, Tsintzas D, Vithoulkas G. 2019. Individualised Homeopathic Therapy in ANCA Negative Rapidly Progressive Necrotising Crescentic Glomerulonephritis with Severe Renal Insufficiency – A Case Report. Journal of Medicine and Life [online]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527409/
https://irisbell.com/about/
Bell, IR. 2020. The Complexity of the Homeopathic Healing Response Part 2: The Role of the Homeopathic Simillimum as a Complex System in Initiating Recovery from Disease. Homeopathy. May;109(2):51-64. Available from: https://pubmed.ncbi.nlm.nih.gov/31785597/
Homeopathy & the Defense system
The human being is a self-organizing complex adaptive system of interconnected networks maintaining life via making constant non-linear dynamic changes on multiple levels concurrently. The defense system exists physically and psychologically within the human being, having the simple goal of preserving life as best as possible.
Homeopathy & Fibromyalgia
Globally one in five people suffer moderate or strong chronic pain, which renders one in three incapable of leading an independent life and one in four stating pain interferes with or destroys relations with family & friends. Pain relief is classed as a human right by WHO.
Homeopathy & Hormonal imbalance
‘It is important we understand homeopathy will not supply deficient hormones nor directly influence the organs in any way rather, homeopathy supports our inherent defense systems to overcome pathologies.’ Dr. Seema Mahesh.
Homeopathy, Athletes, & Antibiotic Resistance
'The nature of our remedies is that different kinds of stress produce different symptomatology, while each remedy can be said to be sensitive to a particular kind of stress.’ Professor George Vithoulkas on Baryta Carbonicum
Howick et al., 2022. Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis. J Clin Epidemiol. Aug;148:160-169. https://pubmed.ncbi.nlm.nih.gov/35447356/
Hamre et al., 2023. Efficacy of homoeopathic treatment: Systematic review of meta-analyses of randomised placebo-controlled homoeopathy trials for any indication. Systematic Rev. Oct 7;12(1):191. https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-023-02313-2#Abs1